Web Analytics

3 Latest Announced Rounds

  • $3,700,000
    Seed
    Technology, Information and Internet
    Apr 3rd, 2025
  • $3,700,000
    Seed
    Technology, Information and Internet
    Apr 3rd, 2025
  • $2,198,930
    Pre-Seed
    Software Development
    Apr 3rd, 2025
$1,373.22M Raised in 49 Funding Rounds in the past 7 Days - View All

Funding Round Profile

Sapreme Technologies BV

start up
Netherlands - Bilthoven, Utrecht
  • 11/10/2021
  • Series A
  • $17,300,000

Sapreme’s mission is to develop next-generation macromolecule therapeutics by circumventing endosomal entrapment, thereby enhancing target engagement. The company’s proprietary endosomal escape platform improves the therapeutic window by enabling access to intracellular targets with minimal toxicity. This approach is applied for Sapreme’s internal pipeline and is available for partnering, without limitation to biologic modality or indication.

Our solution to endosomal entrapment has the potential to re-open myriad drug development pathways for macromolecule therapeutics lacking efficacy and to explore new targets considered “undruggable” by permeabilizing endo-lysosomal membranes, allowing trapped macromolecules to be released, increasing target engagement without negatively impacting the plasma membrane integrity.


Related People

Guy HermansFounder

Guy Hermans Belgium - Merelbeke, Flemish Region

Experienced biopharmaceutical industry executive, with a strong background in target discovery/validation, early stage biologics R&D and platform technology validation and commercialization.

Specialties: Drug target discovery, target validation, product opportunity evaluation, lead discovery project management, clinical immunology, technology development, antibody engineering