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3 Latest Announced Rounds

  • $13,000,000
    Series A

    1 Investors

    Software Development
    Oct 1st, 2025
  • $4,900,000
    Seed

    2 Investors

    Software Development
    Oct 1st, 2025
  • $1,000,000
    Pre-Seed
    Financial Services
    Oct 1st, 2025
$1,285.73M Raised in 63 Funding Rounds in the past 7 Days - View All

Funding Round Profile

Crystalys Therapeutics

start up
United States - San Diego, California
  • 01/10/2025
  • Series A
  • $205,000,000

Crystalys is a clinical-stage biopharmaceutical company transforming the treatment of gout. Co-founded by Novo Holdings and Catalys Pacific, Crystalys brings together a world-class team with deep expertise in gout drug development, dedicated to delivering more effective options for people living with gout.

Dotinurad, the company’s lead candidate and next-generation URAT1 inhibitor with best-in-class potential for safety and efficacy, is being advanced into global Phase 3 trials as a second-line therapy for gout, supported by extensive clinical data from approvals in multiple Asian markets.


Related People

James MackayCo Founder

James Mackay United States - San Diego, California

Distinguished scientist and global life sciences business leader with strong record of bringing multiple drugs to market and patients

|| Strategic thinker with ability to define and implement strategic vision through clear communication and innovative operational delivery

|| Develops strategic and operational partnerships, and builds inspiring cultures via authenticity, development of mutual trust, empowerment and mentoring

|| Creates transparent and open environments allowing staff to raise concerns, cultivating deep thinking, and achieving breakthrough results

|| Experience running large pharmaceutical and small biotechnology businesses with ability to work across international boundaries and cultures, enhancing delivery through diversity

|| Value-driven decision making, the courage to make tough decisions to achieve value-added delivery to the business, and a purposefulness and drive to deliver an outcome that creates positive and lasting change

CAREER HIGHLIGHTS

• Led successful $1.2B acquisition and transition of Ardea Biosciences into AstraZeneca

• Achieved FDA and EMA approval of Zurampic, the first novel MOA for the treatment of gout
in over 50 years

• Led successful commercial licensing of Zurampic and Duzallo to Ironwood Pharmaceuticals and
Grunenthal

• Transformed the AstraZeneca/BMS Diabetes global development and commercial collaboration, and
established Onglyza, Kombiglyze XR and Komboglyze as key growth drivers in the AZ portfolio

• Designed and implemented multiple innovative delivery and partnership models including an
industry leading approach to delivery of outsourced clinical work through development of strategic
partnerships with CROs

• Designed and implemented multiple strategic re-organizations, led major global change
management, whilst delivering improved efficiencies and productivity